BPC-157 | 10 mg | Research Grade Peptide
Full Compound Name: Body Protection Compound-157; Pentadecapeptide BPC-157; PL-10 Molecular Formula: C₆₂H₉₈N₁₆O₂₂ Molecular Weight: 1,419.55 Da CAS Number: 137525-51-0 Purity: ≥98% (HPLC) Appearance: Lyophilized white to off-white powder Quantity: 10 mg per vial
Description
BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide consisting of 15 amino acid residues, derived as a partial sequence analogue of the human gastric juice protein BPC. The compound is stable in aqueous environments across a broad pH range, a physicochemical property that has made it a widely employed model substrate in gastrointestinal and connective tissue biology research conducted in vitro and in preclinical animal models. Its resistance to enzymatic degradation in simulated gastric and intestinal fluids has rendered it a useful investigational tool for studying peptide stability under physiological conditions.
BPC-157 has been the subject of peer-reviewed preclinical research examining its interactions with several signalling pathways, including the nitric oxide (NO) system, vascular endothelial growth factor (VEGF) receptor modulation, and FAK-paxillin pathway activity in cell culture systems. The compound is of academic interest across disciplines including gastroenterology, pharmacology, and tissue biology research.
Amino Acid Sequence
Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val (15 residues; linear; free acid form)
Physicochemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C₆₂H₉₈N₁₆O₂₂ |
| Molecular Weight | 1,419.55 Da |
| Solubility | Soluble in water and aqueous buffer (pH 7.4); acetic acid (0.1%) |
| Form | Lyophilized powder |
| Stability | Stable across broad pH range; resistant to gastric enzymatic degradation in vitro |
| Counter Ion | Acetate or TFA (lot-specific; see CoA) |
Storage Instructions
- Long-term storage: −20°C in a sealed, desiccated environment
- Working aliquots: May be stored at 4°C for up to 7 days once reconstituted; avoid repeated freeze-thaw cycles
- Light sensitivity: Protect from ultraviolet and ambient light at all times; store in original amber vial or wrapped in aluminium foil
- Reconstitution: Reconstitute in sterile deionized water or 0.1% acetic acid; phosphate-buffered saline (pH 7.4) is suitable for aqueous working solutions
- Handling: Use standard laboratory PPE; handle under aseptic conditions appropriate to the research protocol
Documentation
Each vial is supplied with a Certificate of Analysis (CoA) confirming identity, purity (≥98% by HPLC), and mass confirmation by ESI-MS.
⚠ Compliance & Regulatory Statement
This product is intended exclusively for in vitro and laboratory research purposes by qualified scientific personnel. It has not been evaluated, approved, or authorized by Health Canada, the U.S. Food and Drug Administration, or any other regulatory authority for use in humans or animals. This product is not a drug, medicinal product, or dietary supplement, and is not approved for human or veterinary consumption, administration, or therapeutic use of any kind. No health, safety, or efficacy claims are made or implied. The purchaser assumes full responsibility for compliance with all applicable federal, provincial, and local regulations governing the acquisition, handling, storage, and use of research chemicals. For research use only.
